During NREM sleep, the brain is in a self-organized regime in which alternations between spiking and near cessation of spiking propagate along the forebrain, termed slow oscillations (SOs) in the neocortex and SPW-Rs in the hippocampus. Both gain and loss of function studies have demonstrated the importance of tight temporal coordination between SOs and SPW-Rs for systems consolidation, and this temporal coupling has been observed across pairs of regions many synapses removed from one another. However, the spatial extent to which coupling between SPW-Rs and SOs occurs across regions at any one time is unknown, and is of great interest given the multi-modal nature of memories. Taking advantage of the spatial resolution of widefield calcium imaging and temporal resolution of extracellular recordings, we developed a novel chronic preparation in mice that allows simultaneous imaging of all of dorsal neocortex with high-density ipsilateral silicon probe recordings of the hippocampus and retrosplenial cortex, allowing us to monitor multi-scale interaction between regions during sleep. We find interaction between neocortex and hippocampus occurs in three phases, or a neocortical-hippocampal-neocortical loop, with topographic specificity. First, hippocampal SPW-Rs are preceded by increased fluorescence in mouse visual and association cortices, or mouse default mode network (DMN). The number of cortical regions active preceding the SPW-R predicts the magnitude of sharp wave associated with the ripple, which is thought to reflect the degree of input to the region. The greater the magnitude of input, the larger the amplitude of the evoked ripple, and the larger the DOWN state evoked in the DMN. This evoked DOWN state is most likely to occur in retrosplenial cortex, and the extent to which it propagates down the cortical hierarchy varies as a function of the depth of NREM.