Learning requires the formation or modification of neural circuits – an extraordinary showcase of the brain’s plasticity. Despite an established appreciation for the reorganizational capabilities of the brain, the exact mechanisms that enable experience-dependent plasticity remain unknown. The goal of this work is to uncover how circuitry of the auditory cortex (AC) facilitates learning of an auditory-driven maternal retrieval behavior in mice. Mouse pups emit ultrasonic vocalizations (USVs) when they are separated from the nest which cues maternal retrieval - a learned response to these distress cries. Interestingly, the transcription factor methyl-CPG binding protein 2 (MeCP2) is required for successful retrieval1. Furthermore, a subpopulation of inhibitory cells, parvalbumin-positive (PV) interneurons, is particularly susceptible to MeCP2 perturbations. Females with an MeCP2 mutation (a Rett Syndrome model) exhibit deficits in pup retrieval, have elevated PV expression, and significantly more perineuronal nets encompassing AC PV cells - a hallmark signaling the closure of plasticity periods1. This suggests that disruptions to the PV inhibitory circuitry of the AC underlie deficits in retrieval by limiting the cortical plasticity necessary to learn this behavior. However, PV activity has never before been probed during retrieval. Here, we aim to uncover the real-time PV network contributions to retrieval, and how disruptions to the network impair behavior. We used fiber photometry in the AC PV population during retrieval behavior in both wildtype and MeCP2 mutant females. AC PV activity was highly dynamic throughout the retrieval session in wildtypes, but not MeCP2 mutants. We found pronounced peaks in AC PV activity during both auditory events (USVs) and behavioral epochs such as the mouse contacting pups. This prompted us to implement a general linear model to uncover the signal’s sensory and behavioral influences. In parallel, we are considering these peaks to reflect an attentional PV network state that may facilitate successful retrieval.