Sensory information is first processed by various thalamic nuclei before reaching the pallium in amniotes, where it is used for higher-order computations such as integrating diverse sensory information that can be utilized to form associations. In teleost fish, the dorsal thalamic nuclei, believed to be analogous to the amniote thalamus, projects primarily to the subpallium. However, the major diencephalic input to the pallium originates from the preglomerular nucleus (PG), suggesting that it may perform analogous functions to the amniote thalamocortical pathway. To examine this, we first mapped the anatomical inputs to the zebrafish PG and showed that it receives inputs from multiple sensory and limbic forebrain and midbrain nuclei while massively projecting to the pallium, resembling the thalamic equivalent in other species. Using in vivo two-photon Ca2+ imaging in juvenile zebrafish, we showed that PG neurons preferentially respond to distinct sensory stimuli (light vs mechanical vibrations). Calcium imaging of the PG axon terminals in the zebrafish pallium revealed that different sensory modalities elicit responses in mutually exclusive and topographically distinct pallial zones. Both the sensory evoked and resting state activity of the PG and PG axon terminals were topographically organized into distinct zones, further supporting the partitioning of PG into distinct sensory selective and functional submodules. Additionally, micro-electrode stimulation of PG activated neurons in topographically restricted zones in the dorsal lateral (hippocampal analogue) and dorsal medial (amygdala analogue) pallium. In contrast to the PG neurons and axon terminals, pallial neurons exhibited mixed selectivity to multiple sensory modalities. Moreover, we observed diverse non-linear interactions between visual and mechanical vibrations stimuli, across spatially defined subregions of the pallium. Our results revealed that similarly to the thalamocortical systems in mammals, the zebrafish pallium integrates sensory information in a hierarchical manner from the thalamic-like PG and can potentially use this for higher cognitive operations.