The Autism Spectrum Disorder (ASD) is a pervasive neurodevelopmental condition, more prevalent in males, characterized by social behavior impairments. Exposure to valproic acid (VPA) during pregnancy is linked to ASD. In our VPA-mouse model experiment, we examined neuronal activation in the social decision-making network (SDMN) and stress-regulatory nuclei in the brain of juvenile male mice across diverse social settings. VPA treatment effectiveness was validated through a three-chamber sociability test, a standard method for measuring ASD-like behavior. WE used c-Fos immunohistochemistry to capture cell activity during social situations, whether mice cohabited with familiar companions or experienced a day's separation followed by reinstatement to familiar cagemates. Unlike analyzing separate nuclei, we focused on functional connectivity changes between VPA treatment and control (CTR). Functional brain networks were formed by correlating SDMN areas and stress-regulating nuclei’s c-Fos activity. We then analyzed strength within and between perviously identified subnetworks. In social behavioral analysis, VPA-treated animals exhibited more correlation of nuclei activity with aversive behaviors compared to CTR animals, which showed more correlations with prosocial behaviors. Our findings suggest that VPA-treated animals have a more widespread functional connectivity network than controls, with most subnetworks showing stronger connections, except the social network. Network-hub (betweenness) analysis revealed less dominance of SDMN nuclei related to regulating social stress in VPA-treated animals. Exposure to valproic acid likely disrupts the neural connectivity, impacting social interactions from early postnatal development and hindering the acquisition of normal social behavior.