The appearance of image-forming eyes enabled animals to use vision for advanced behavioural repertoires, as constantly redirecting their gaze away or towards relevant targets. To prevent image blurring, mechanisms to stabilize the world in the retina are required. The vestibulo-ocular and the optokinetic reflexes are the main contributors to gaze stabilization, by generating compensatory movements, while the optic tectum integrates multisensory information and generates orienting/evasive gaze movements in all vertebrates. We use the lamprey, oldest extant vertebrate that shows remarkable similarities with other vertebrates in gaze control, to analyse the neuronal pathways underlying visuo-vestibular integration, and to investigate how gaze stabilizing and goal-directed movements interact. For this purpose, we developed an innovative and complex experimental platform, using a lamprey eye-brain-labyrinth preparation. This setup allows different vestibular stimulations with rotational and translational movements on several axes, combined with optokinetic and non-optokinetic visual stimulation, via screens, working as a simple virtual reality. While stimulating we can record neural activity, enabling us to analyse the visuo-vestibular integration in the brain, and monitor by video analysis or electromyograms the evoked motor responses of complex visuo-vestibular paradigms simulating swimming episodes, without the influence of motor commands. We want to compare the ex vivo experiments with the real swimming behaviour of lampreys in their environment. These animals are photophobic, but studies analysing their behaviour in response to different visual stimuli are very scarce. Thus, we are conducting behavioural experiments, with different light/dark paradigms at different life stages, to analyse, by video tracking, different visuomotor behaviours.