The hippocampus is thought to form the brain substrate of a cognitive map. While the spatial component of this map involves hippocampal ‘place’ cells, non-spatial features may require coupling with other brain areas. This could involve ‘hippocampal sequences’, endogenous activations of successive place cells representing entire trajectories at a highly accelerated rate. These sequences are paced by theta or ripple oscillations, and could participate in learning and memory, as well as goal-directed decision making. However, the association between hippocampal sequences and reward- and goal-related signals remains poorly understood. The ventral tegmental area (VTA) and nucleus accumbens (Nacc) are involved in reward coding and goal-directed action selection, and have both been independently reported to activate during hippocampal ripples. These co-activations could be part of a broader mechanism, whereby the three structures coordinate at a precise timescale during hippocampal oscillations, with different characteristics depending on cognitive function.To explore these questions, we performed electrophysiological recordings from dozens of single units in the dorsal hippocampus, NAcc and VTA simultaneously, in rats trained to learn a complex spatial memory task in the ‘Hippodamos maze’: this novel task features a daily-changing set of reward and error zones, requiring the rats to learn elaborate spatial configurations, to flexibly adapt to changes in these configurations, and every day learn and remember trajectories never experienced before. We investigate how the hippocampus, NAcc and VTA coordinate during various cognitive functions (learning, recall, planning, long-term storage, etc.) and relate to the performance of the animals in the task.