Performance of goal directed actions requires integration of motor commands with their expected sensory outcome. A prominent theory suggests that predictions of actions’ sensory outcome (‘efference copies’) are sent to relevant sensory regions and modulate their neural state, resulting in differential processing of the reafferent sensory signal. However, predictive signals are not unique to actions and can be associated with non-motor sources as well. It is an open question whether motor and non-motor predictive signals share common neural mechanisms. To address this question, we used fMRI and presented participants with visual stimuli that were preceded by either a button press or a tone. We compared the activity in visual cortex for identical visual stimuli between the two predictive cue conditions. Results suggest that activity in visual cortex is sensitive to the type of cue (motor/auditory). In addition, we examined sensitivity of motor/auditory cortices to the coupling with a visual outcome. To this end, we asked participants to press buttons and listen to tones that were not followed by visual consequences. Both in motor and in auditory cortices, we find stronger fMRI activity when the event (button press/auditory tone respectively) is not coupled with an upcoming visual outcome. Taken together, these results suggest that coupling with a sensory outcome affects both processing of the cue and processing of the outcome, in a modality-specific manner. These results may help shape models of predictive mechanisms across modalities.