Background: The corticolimbic tract (CLT), encompassing subcortical and neocortical areas, is linked to socioemotional skills such as emotion processing and regulation. Alterations in CLT structure, function, and connectivity are associated with socioemotional deficits and are reported for different psychopathologies. An increased knowledge of the mechanisms supporting healthy CLT development, including biological and environmental factors, may further our understanding of socioemotional disorders in childhood and adolescence, ultimately impacting early identification and treatment. Here, we aim to describe the developmental trajectories of the CLT and test intergenerational transmission. Methods: This was achieved by inclusion of 157 children, ages 6-14 years (from own studies [n=101/42 females] and by addition of data from the Healthy Brain Network [n=54/16 females]) and by use of intergenerational neuroimaging data collected in 91/48 mother-child/father-child dyads. All structural T1-weighted MPRAGE data was preprocessed in Freesurfer and gray matter CLT volume was extracted for subcortical (i.e., amygdala, hippocampus, nucleus accumbens) and neocortical (i.e., anterior cingulate and medial orbitofrontal cortices) regions. Results: First results reveal region-specific, age-dependent CLT trajectories (Fig.1). Furthermore, parent-child CLT similarity was greater as compared to non-related adult-child dyads (tested through Pearsons correlation and permutations, controlling for childrens sex and age). In a first group of mother-child dyads (n=39), similarity of the CLT and mental-health were correlated. Further analyses, including well-being, families’ closeness and time spent together are ongoing. Conclusion: Our data informs about early CLT development, illustrates age-specific trajectories in gray matter volume, and demonstrates a significant intergenerational CLT transmission through neuroimaging in parents and their children.