The prefrontal cortex is involved in cognitive flexibility. Independently of the task, individual and concerted neuronal activity is related to behaviour, task episodes, and prediction of future choices. However, not every choice arises from the same motivation. Choices can be spontaneous, based on information from previous experience, or querying for additional information. What are the neuronal dynamics governing these possibilities? We simultaneously record hundreds of individual neurons from the mouse prefrontal cortex using silicon probes. Head-fixed animals engage in a probabilistic 2-sided choice task to encourage behavioural adaptation. One choice is considered safe with the reward amount fixed and given with a probability of 90% during the entire session. The other choice is considered a gamble, for which the reward amount is larger and the probabilities of receiving a reward change during the session. During periods with identical behavioural output (consecutive trials with the same choice and reward outcome), the choice behaviour of mice is not always the same, suggesting at least two types of choices: a fast direct one and a slower indecisive one. By analysing the recorded neuronal activity during task performance, we found distinct prefrontal firing patterns depending on the type of choice. Thus, in addition to task episode-related firing patterns (e.g., response to reward or choice), prefrontal activity is dynamically regulated depending on the animal's motivation behind the choice.Funding: Grant I 5458 - Austrian Science Fund; FOR5159 - German Research Foundation