Most children with developmental coordination disorders have sensorimotor impairments and reduced physical activity, which can lead to cognitive and motor disorders. On the contrary, physical activity is widely known for its beneficial effects on the body, especially during childhood. Indeed, physical activity is essential for the development of the neuromuscular system, allowing the acquisition of coordination and increasingly precise movements during the first years of life. In order to better understand the effects of atypical sensorimotor experiences during childhood, a model of early sensorimotor restriction (SMR) was developed in rats. This model consists in casting pups hindlimbs from birth until postnatal day 28 (P28). Previous studies have shown that SMR had enduring effects on motor function. Our aim was to determine whether physical activity from P28 to P60 could reverse adverse effects of early SMR. To that purpose, at P28, control and SMR rats were housed in standard cage (sedentary group) or in enriched cages with access to an activity wheel for one hour/day (exercise group). Motor function was evaluated using Catwalk XT and Rotarod. Preliminary results show that the activity (evaluated by distance in activity wheel and in actimeter) is sex-dependent. In addition, the Rotarod performance is altered in SMR rats but an improvement is observed from P28 to P60 that correlates with activity level. In addition, early SMR alters some gait parameters, and exercise partially reverses these changes. In conclusion, physical activity seems to be an interesting strategy to restore motor performance after a hypoactivity during childhood.