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Authors & Affiliations
Jan Cimbalnik, Jaromir Dolezal, Pavel Daniel, Martin Kojan, Lena Jurkovicova, Robert Roman, Wladyslaw Sredniawa, Wojciech Fortuna, Monika Sluzewska, Katarzyna Smarzewska, Peter Reinacher, Artur Weiser, Tymoteusz Skok, Tomasz Piernicki, Aleksandra Orzol, Amanda Lier, Sahar Seifzadeh, Marina Galanina, Bozena Kostek, Andrzej Czyzewski, Pawel Tabakow, Milan Brazdil, Michal Kucewicz
Abstract
Intracranial human brain recordings from multiple stereotactically implanted depth electrodes using stereo-EEG (sEEG) technology for seizure localization provides unique local field potential signals (LFP) sampled with standard macro- and special micro-electrode contacts. Over one hundred macro- and micro-contact LFP signals localized in particular brain regions were recorded from each sEEG monitoring case as patients engaged in an automated battery of verbal memory and non-verbal gaze movement tasks. Subject eye and vocal responses in both visual and auditory task versions were automatically detected in English, Polish, Czech and Slovak languages with accurate timing of the correct and incorrect verbal responses using our web-based transcription tool. The behavioral events, LFP and pupillometric signals were synchronized and stored in a standard BIDS data structure with corresponding metadata. Each dataset contains recordings from at least one battery task performed over at least one day. The same set of 180 common nouns in the three languages was used across different battery tasks and recording days to enable analysis of selective responses to specific word stimuli. Our preliminary data analysis shows evidence of:1. Strong subsequent memory effects in the pupil dilation between good and poor trials of free recall2. High frequency oscillations correlated with pupil dilation around free recall of memorized word stimuli3. Coincident bursting of high frequency oscillations across the cortex preceding free memory recall4. Consistent responses to particular words across different tasks and days of recordings5. High yields of single units firing throughout the battery tasks