Internal states flexibly shape social behaviour. Females across species for instance become more receptive during Estrus, more parental during pregnancy, and more aggressive during hunger. While most research has focussed on the behavioural role of individual internal states, animals exhibit multiple states at any given time. How and where the brain integrates combinations of states to shape behaviour remains largely unknown. Here we report that hunger and estrous state together orchestrate a switch to pup-directed aggression in female mice. This behavioural switch results from inhibition of the medial preoptic area (MPOA) by Agouti-related protein-expressing neurons in the arcuate nucleus of the hypothalamus (ArcAgRP neurons). However, switching probability is set by integrating progesterone (P4)-to- estradiol (E2) ratio by MPOA neurons throughout the estrous cycle. We found that hunger and hormonal states converge on a specific membrane current in MPOA neurons – Ih – mediated by HCN channels. While ArcAgRP neurons silence MPOA neurons via inhibition of Ih, P4/E2 ratio tunes MPOA neuronal excitability by regulating HCN channel expression. We are currently investigating how hunger and hormonal states cooperatively set behavioural switching probability in the MPOA using in vivo imaging in freely behaving animals. Our preliminary experiments indicate that episodes of aggression can be distinctly identified as separate neural states which exhibit a low dynamic velocity, suggesting a potential impact on the stability of animals' behavioural choices. We hypothesize that the interaction between hunger and hormonal states may alter neural trajectories in dynamic spaces, increasing the chances of reaching this stable state of aggression.