Although much work has been devoted to studying the function of molecularly-defined subtypes of GABAergic interneurons in circuits and behaviors, it has been debated if cells belonging to the same molecular and morphological type, for example parvalbumin-expressing basket cells, do homogeneously engage in circuit operations in behaving animals. This can only be studied if the identity of the recorded cell is unambiguously determined. We have established a method to optotag juxtacellularly-recorded neurons in freely-moving rats performing a decision-making task to investigate the operational heterogeneity of individual interneurons in the orbitofrontal cortex. In extracellular recordings, putative interneurons are mostly classified based on features such as spike width and firing frequency. Such criteria bias the identification of putative interneurons to fast-spiking cells, often parvalbumin-expressing basket cells. Our preliminary results show that, based on these criteria, a large number of interneurons can be misclassified as regular-spiking, wide-spike putative pyramidal neurons. Second, our data show that the firing behavior of individual orbitofrontal interneurons, recorded for periods of tens to hundreds of individual decision-making trials, tends to remain constant over the entire period. Ongoing analyses of the juxtacellularly-labeled cells will allow us to determine whether interneurons of the same type do homogeneously engage in choice- and task-related episodes. These data will provide critical evidence for understanding how interneurons contribute to the formation of pyramidal cell ensembles during flexible decision making.