In the adult brain, subsets of astrocytes act as neural stem cells in two specialized niches, the sub-ventricular zone and hippocampal dentate gyrus, where they produce olfactory bulb interneurons and dentate gyrus granule cells throughout life. In specific conditions the genesis of new neurons can occur also outside these niches in the adult brain parenchyma. This ectopic neurogenesis is prominent in the striatum where it occurs in both physiologic, in adult rabbits and adolescent guinea pigs, or pathologic conditions, such as mouse models of both progressive and acute neuronal degeneration. However the phenotypic commitment of the activated progenitors is still unclear: in all analysed models their neuronal progeny live transiently and do not express markers of either mature or immature striatal neuron types. Unpublished results (see poster of Nato et al.) further shows that despite their transient life these cells can integrate into the pre-existing circuits. Here we used single cell RNAseq to analyze the identity striatal neuroblasts induced by excitotoxic lesion in mice. In this model we previously demonstrated that newly generated neurons are exclusively generated by local astrocytes. Our data of indicate that these neuroblasts belong to the class of lateral ganglionic eminence (LGE)-derived GABAergic interneurons and are clearly segregated from striatal projection neurons (LGE-derived) or striatal interneurons (MGE-derived). Thus, astrocyte-generated neurons in the striatum do not replace degenerated cells but still transiently integrate in pre-existing circuitry, thereby potentially taking part in post-lesion network plasticity supporting functional recovery after damage.