The perirhinal cortex (PER) integrates and transfers information from cortical areas to the hippocampus, which is crucial for memory-related tasks, particularly novel object recognition. However, how the PER gates information transfer is largely unknown. During learning and novelty-induced exploration, the locus coeruleus releases noradrenaline, a candidate for modulating synaptic plasticity within the PER. We explored the hypothesis that noradrenaline could transiently increase the excitability of the PER network, enhancing information transfer toward the hippocampus and ultimately leading to improved performances in the novel object recognition task.Whole-cell patch-clamp recordings were performed on ex-vivo brain slices of mice to record the effect of noradrenaline on principal neurons in the superficial layers of the PER. Measurements included changes in intrinsic excitability, spontaneous synaptic events, and evoked synaptic currents for the determination of the balance between excitation and inhibition.While the application of noradrenaline did not alter the intrinsic excitability of PER neurons, it increased the frequency of miniature excitatory postsynaptic currents (mEPSCs), without affecting miniature inhibitory postsynaptic currents (mIPSCs). In addition, evoked stimulation of the insular cortex activated the PER network, and the resulting evoked synaptic conductances were decomposed into their excitatory and inhibitory components. Noradrenaline shifted this excitation/inhibition balance of PER neurons towards excitation. This study shows that noradrenergic modulation of the PER network increases its excitability, which may increase the chance for information transfer to the hippocampus and ultimately lead to increased performances in memory tasks.