Post-DocApplications Closed

Prof. Dr. S.E. Fisher

Nijmegen, Netherlands
Apply by Dec 15, 2021

Application deadline

Dec 15, 2021

Job

Job location

Prof. Dr. S.E. Fisher

Geocoding

Nijmegen, Netherlands

Geocoding in progress.

Source: legacy

Quick Information

Application Deadline

Dec 15, 2021

Start Date

Flexible

Education Required

See description

Experience Level

Not specified

Job

Job location

Prof. Dr. S.E. Fisher

Geocoding

Nijmegen, Netherlands

Geocoding in progress.

Source: legacy

Map

Job Description

The successful candidate will join an innovative research program that is characterizing individual variation in language skills at behavioural, neurobiological, and genetic levels, an initiative of the Language in Interaction (LiI) consortium, sponsored by a major grant from the Netherlands Organisation for Scientific Research. The LiI consortium has developed a computer-based test battery to assess core skills underlying speaking and listening across a broad spectrum of abilities, and has already applied this to hundreds of young adults from the general population, a subset of whom are also tested with functional MRI. In parallel, saliva sampling has been used to collect DNA. The postdoctoral scientist will take the lead on the genetic aspects of the project. Specifically, they will process and analyse genome-wide genotype data from this unique resource, and use methods for analyzing polygenic contributions to human traits in order to trace genetic links to cognitive skills, childhood learning disorders, and MRI-based measures of brain structure/function, integrating with independent datasets available at the Language and Genetics department. The project will be further scaled up by applying online versions of the LiI battery to large pre-existing population-based cohorts with available genome-wide genotypes. The postdoctoral scientist will also foster connections to ongoing work by GenLang, an international network of researchers carrying out genetic association meta-analyses of multiple speech/language/reading-related cohorts across the world.

Requirements

  • You are a research scientist who holds
  • or shortly expects to obtain
  • a PhD in a field with direct relevance for studying genomics of complex (human) traits in large-scale datasets. You are proficient in coding/scripting and statistics
  • and sufficiently experienced that you can readily use bioinformatics and statistical genetics methods
  • such as genome-wide association screening
  • genetic correlations
  • polygenic score analysis
  • pathway enrichment
  • and interrogation of diverse ‘omics’ resources. You have a critical and careful approach to science
  • and you strive for robustness and reproducibility of results. You are highly organized and adept in communicating project plans and outcomes to others
  • in both spoken and written form. You are interested in working together with researchers from a wide range of backgrounds
  • and in helping to drive projects of large consortia. The successful candidate will be involved in supervising junior scientists
  • including students and research assistants
  • and in writing up findings for publication
  • as well as giving presentations about the work at international conferences.