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Seminar✓ Recording AvailablePhysics of Life

Flow singularities in soft materials: from thermal motion to active molecular stresses

Mehdi Molaei

Dr.

Pritzker School of Molecular Engineering, University of Chicago

Schedule
Monday, August 16, 2021

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Schedule

Sunday, August 15, 2021

5:00 PM America/Los_Angeles

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Host: SLAAM by UC Merced

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223642

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Event Information

Domain

Physics of Life

Original Event

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Host

SLAAM by UC Merced

Duration

70 minutes

Abstract

The motion of passive or active agents in soft materials generates long ranged deformation fields with signatures informed by hydrodynamics and the properties of the soft matter host. These signatures are even more complex when the soft matter host itself is an active material. Measurement of these fields reveals mechanics of the soft materials and hydrodynamics central to understanding self-organization. In this talk, I first introduce a new method based on correlated displacement velocimetry, and use the method to measure flow fields around particles trapped at the interface between immiscible fluids. These flow fields, decomposed into interfacial hydrodynamic multipoles, including force monopole and dipole flows, provide key insights essential to understanding the interface’s mechanical response. I then extend this method to various actomyosin systems to measure local strain fields around myosin molecular motors. I show how active stresses propagate in 2d liquid crystalline structures and in disordered networks that are formed by the actin filaments. In particular, the response functions of contractile and stable gels are characterized. Through similar analysis, I also measure the retrograde flow fields of stress fibers in single cells to understand subcellular mechanochemical systems.

Topics

active materialsactomyosin systemscorrelated displacement velocimetryflow fieldshydrodynamicsinterfacial hydrodynamic multipolesmolecular motorsretrograde flowself-organizationssoft materialssoft-materials

About the Speaker

Mehdi Molaei

Dr.

Pritzker School of Molecular Engineering, University of Chicago

Contact & Resources

Personal Website

www.linkedin.com/in/mehdi-molaei/

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