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CNRS, Institut des Maladies Neurodégénératives, Bordeaux, France
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Schedule
Thursday, December 10, 2020
2:00 PM Europe/Zurich
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Format
Past Seminar
Recording
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Host
NeuroLeman Network
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Human neuroimaging research has consistently shown that drug addiction is associated with structural and functional changes within the orbitofrontal cortex (OFC). In view of the important role of the OFC in value-based decision-making, these changes have been hypothesised to bias choice towards drug use despite and at the expense of other competing pursuits, thereby explaining drug addiction. Here I will present in vivo recording data in the OFC supporting this hypothesis in a choice-based model of addiction where rats could choose between two actions, one rewarded by a drug (cocaine or heroin), the other by a nondrug alternative (saccharin).
Karine Guillem
CNRS, Institut des Maladies Neurodégénératives, Bordeaux, France
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