Cookies
We use essential cookies to run the site. Analytics cookies are optional and help us improve World Wide. Learn more.
PhD student at the University of Cambridge, United Kingdom.
Showing your local timezone
Schedule
Tuesday, August 26, 2025
2:00 AM America/Santiago
Domain
Open SourceHost
LIBRE hub Seminar
Duration
60 minutes
Advancements in imaging speed, depth and resolution have made structured illumination microscopy (SIM) an increasingly powerful optical sectioning (OS) and super-resolution (SR) technique, but these developments remain inaccessible to many life science researchers due to the cost, optical complexity and delicacy of these instruments. We address these limitations by redesigning the optical path using in-line fibre components that are compact, lightweight and easily assembled in a “Plug & Play” modality, without compromising imaging performance. They can be integrated into an existing widefield microscope with a minimum of optical components and alignment, making OS-SIM more accessible to researchers with less optics experience. We also demonstrate a complete SR-SIM imaging system with dimensions 300 mm × 300 mm × 450 mm. We propose to enable accessible SIM imaging by utilising its compact, lightweight and robust design to transport it where it is needed, and image in “unconventional” environments where factors such as temperature and biosafety considerations currently limit imaging experiments.
Rebecca McClelland
PhD student at the University of Cambridge, United Kingdom.
Contact & Resources
open source
La resonancia magnética nuclear está basada en el fenómeno del magnetismo nuclear que más aplicaciones ha encontrado para el estudio de enfermedades humanas. Usualmente la señal de RM es recibida y tr
open source
High-quality glass lenses are commonplace in the design of optical instrumentation used across the biosciences. However, research-grade glass lenses are often costly, delicate and, depending on the pr
open source
What’s the point of having scientific and technological innovations when only a few can benefit from them? How can we make science more inclusive? Those questions are always in the back of my mind whe