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SeminarPast EventNeuroscience

Some new insights into the central sensing of nutritional state and somatic stress

Stephen O'Rahilly

Prof.

Wellcome-MRC Institute of Metabolic Science, University of Cambridge

Schedule
Monday, June 28, 2021

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Schedule

Monday, June 28, 2021

4:00 PM Europe/Lisbon

Host: Brain-Body Interactions

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Event Information

Domain

Neuroscience

Original Event

View source

Host

Brain-Body Interactions

Duration

70 minutes

Abstract

This talk will focus on two areas. I will firstly discuss some new data, starting with insights from rare human genetic variants, which helps to clarify the role of the central melanocortin system in the acquisition of nutrients and their disposition into growth, the acquisition of lean mass and sexual maturation . I will then discuss some aspects of the emerging biology of GDF15; a sentinel hormone conveying information regarding a range of somatic stresses to the brain.

Topics

GDF15central melanocortin systemhormone signalinghuman genetic variantshuman geneticslean massmetabolismnutrient acquisitionnutritional stateobesitysexual maturationsomatic stress

About the Speaker

Stephen O'Rahilly

Prof.

Wellcome-MRC Institute of Metabolic Science, University of Cambridge

Contact & Resources

Personal Website

www.mrl.ims.cam.ac.uk/research/principal-investigators/professor-sir-stephen-orahilly/

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