Royal Swedish Academy of Sciences

Joel Mokyr, Philippe Aghion and Peter Howitt examine why technological innovation can sustain economic growth despite the disruption it creates. Mokyr considers the historical development of useful knowledge, the connection between understanding and invention, and the institutional and political conditions needed for continuing progress. Aghion develops the economics of creative destruction, connecting innovation incentives with entry, incumbent firms and competition. He discusses how theoretical models and empirical evidence inform policies intended to support productivity growth. Howitt explains the development of the creative-destruction growth model and explores implications for competition, patent policy, international trade and technological change. The lectures also consider artificial intelligence and employment, distinguishing the historical resilience of growth from uncertainty about new forms of automation.

Richard Robson, Susumu Kitagawa and Omar M. Yaghi examine the origins, development and applications of metal–organic frameworks. Robson follows the emergence of coordination polymers and the design of extended molecular structures from pre-organized building blocks, explaining the architectural ideas behind framework construction. Kitagawa describes how coordination chemistry led to porous materials and then to flexible crystalline structures. His discussion of soft porous crystals shows how frameworks can respond to external stimuli, opening and closing as they capture molecules, with implications for gas storage and separation. Yaghi considers how fundamental framework chemistry can connect to industrial and societal applications, including emerging uses of artificial intelligence. Together, the lectures show how complementary approaches to molecular design, porosity and responsive structure developed into a broad materials research field.

John Clarke, Michel H. Devoret and John M. Martinis trace the discovery that a macroscopic electrical circuit can display quantum tunnelling and discrete energy levels. Clarke connects early superconducting measuring devices with experiments on current-biased Josephson junctions. Microwave-induced resonances and the crossover from thermal activation to temperature-independent escape provide tests of quantum behaviour. Devoret explains how superconducting circuits became controllable artificial atoms, with Josephson elements enabling engineered energy spectra, qubits and quantum-limited amplifiers. He considers what these designed systems make possible beyond experiments with natural atoms. Martinis follows the development from early junction experiments to superconducting quantum processors. He discusses energy-level quantization, tunnelling, photon generation, quantum computational experiments, and the fabrication and error-control challenges involved in building useful machines.