Social Defeat
social defeat
Decoding stress vulnerability
Although stress can be considered as an ongoing process that helps an organism to cope with present and future challenges, when it is too intense or uncontrollable, it can lead to adverse consequences for physical and mental health. Social stress specifically, is a highly prevalent traumatic experience, present in multiple contexts, such as war, bullying and interpersonal violence, and it has been linked with increased risk for major depression and anxiety disorders. Nevertheless, not all individuals exposed to strong stressful events develop psychopathology, with the mechanisms of resilience and vulnerability being still under investigation. During this talk, I will identify key gaps in our knowledge about stress vulnerability and I will present our recent data from our contextual fear learning protocol based on social defeat stress in mice.
The analyses of neural basis for individual differences in behavioral outcomes caused by long-term social defeat stress in mice
FENS Forum 2024
Brain-wide scale neuronal activation of behavioral outcomes following learned helplessness and acute social defeat stress in mice
FENS Forum 2024
Female microglia and neurogenesis respond differently to social defeat stress compared to males
FENS Forum 2024
Intermittent access to a high-fat diet blocks the increase in ethanol consumption and the neuroinflammatory response induced by social defeat in adult male mice
FENS Forum 2024
Ketogenic diet buffers brain gene expression and ethanol consumption induced by vicarious social defeat exposure in female mice
FENS Forum 2024
Raphe nucleus function in aversive valence processing between adaptive learning and social defeat in zebrafish
FENS Forum 2024
Role of the medial amygdala glutamatergic and GABAergic neurons during social defeat
FENS Forum 2024
TPH2 knockout rats cannot accept social defeat in resident-intruder test
FENS Forum 2024