Activity dependent myelination: a mechanism for learning and regeneration?
Thóra Káradóttir · WT-MRC Stem Cell Institute, University of Cambridge
Tue, Oct 12, 2021 · 15:00 UTC
The CNS is responsive to an ever-changing environment. Until recently, studies of neural plasticity focused almost exclusively on functional and structural changes of neuronal synapses. In recent years, myelin plasticity has emerged as a potential modulator of neural networks. Myelination of previously unmyelinated axons, and changes in the structure on already-myelinated axons, can have large effects on network function. The heterogeneity of the extent of how axons in the CNS are myelinated offers diverse scope for dynamic myelin changes to fine-tune neural circuits. The traditionally held vi