Topic: Exploratory research

NIH PA-25-304 supports exploratory biomedical, behavioral and clinical research at an early conceptual stage, including risky approaches, new methods and models. Clinical trials are not permitted. Projects must fit a participating NIH institute or center. The next new-application deadline is October 16, 2026 at 5 p.m. in the applicant organization’s local time; the next resubmission deadline is November 16. Direct costs are limited to USD 275,000 over two years and USD 200,000 in any one year. Apply through ASSIST, Grants.gov Workspace or an institutional system; organizational registrations a

The goal of this talk is to first provide a realization of why the replication crisis is omnipresent and then point to several tools via which the listener can improve their own work. To do so, I will go through our own work on social thermoregulation, point out why I thought changes were necessary, discuss which shortcomings we have in our own work, which measures we have taken to reduce those shortcomings, which tools we have relied on to do so, and which steps I believe we still need to make. Specifically, I will go through the following points: Major replication failures and data fabricati