Flexible motor sequence generation by thalamic control of cortical dynamics through low-rank connectivity perturbations
Laureline Logiaco · Center for Theoretical Neuroscience, Columbia University
Wed, Mar 9, 2022 · 17:35 UTC
One of the fundamental functions of the brain is to flexibly plan and control movement production at different timescales to efficiently shape structured behaviors. I will present a model that clarifies how these complex computations could be performed in the mammalian brain, with an emphasis on the learning of an extendable library of autonomous motor motifs and the flexible stringing of these motifs in motor sequences. To build this model, we took advantage of the fact that the anatomy of the circuits involved is well known. Our results show how these architectural constraints lead to a prin