adipose tissue

Sympathetic nerve remodeling in adipose tissue

Sympathetic nerve activation of adrenergic receptors on fat is the major pathway the brain uses to drive non-shivering thermogenesis in brown adipose tissue and lipolysis in white fat. There is accumulating evidence that the peripheral nerve architecture inside of organs is plastic (can be remodeled) but the factors and conditions that regulate or result in remodeling are largely unknown. Particularly for fat, it remains unclear if nerves in fat can be remodeled in step with hyperplasia/trophy of adipose tissue as result of a prolonged energy surfeit. This talk will discuss our recent work identifying the sympathetic nerve architecture in adipose tissue as highly plastic in response to the adipose hormone leptin, the brain circuitry leptin acts on to regulate this and the physiological effects remodeling of innervation has on fat tissue function.

Functional recovery caused by human adipose tissue mesenchymal stem cell-derived extracellular vesicles administered 24h after stroke in normotensive rats and some differences to hypertensive rats

Late, but not early active-phase forced wheel running prevented visceral adipose tissue gain without chronic hypothalamic changes during the adolescence of Sprague-Dawley rats

TRH Neurons in Energy Homeostasis and Regulation of Brown Adipose Tissue

Adipose tissue and adipokine variations are linked to structural gray and white matter changes

FENS Forum 2024

Effects of flavonoids on adipose tissue/microglia cross-talk

FENS Forum 2024

Exploring the relationship between adipose tissue and Alzheimer's disease pathogenesis

FENS Forum 2024

Preoptic PNOC neurons modulate energy expenditure and adipose tissue function

FENS Forum 2024

The role of TRH neurons in energy homeostasis and regulation of brown adipose tissue

FENS Forum 2024