affective biases

Unmotivated bias

In this talk, I will explore how social affective biases arise even in the absence of motivational factors as an emergent outcome of the basic structure of social learning. In several studies, we found that initial negative interactions with some members of a group can cause subsequent avoidance of the entire group, and that this avoidance perpetuates stereotypes. Additional cognitive modeling discovered that approach and avoidance behavior based on biased beliefs not only influences the evaluative (positive or negative) impressions of group members, but also shapes the depth of the cognitive representations available to learn about individuals. In other words, people have richer cognitive representations of members of groups that are not avoided, akin to individualized vs group level categories. I will end presenting a series of multi-agent reinforcement learning simulations that demonstrate the emergence of these social-structural feedback loops in the development and maintenance of affective biases.

Modelling affective biases in rodents: behavioural and computational approaches

My research focuses, broadly speaking, on how emotions impact decision making. Specifically, I am interested in affective biases, a phenomenon known to be important in depression. Using a rodent decision-making task, combined with computational modelling I have investigated how different antidepressant and pro-depressant manipulations that are known to alter mood in humans alter judgement bias, and provided insight into the decision processes that underlie these behaviours. I will also highlight how the combination of behaviour and modelling can provide a truly translation approach, enabling comparison and interpretation of the same cognitive processes between animal and human research.

Effect of amitriptyline on affective biases in male rats

Differences between first- and second-generation antidepressants and modulation of affective biases in Lister Hooded rats

FENS Forum 2024