alcohol use disorder

Role of the gut microbiota in the development of alcohol use disorder

The gut microbiota is composed of a very large number of bacteria, viruses, fungi and yeasts that play an important role in the body, through the production of a series of metabolites (including neurotransmitters), and through an essential role in the barrier function of the gut and the regulation of immunity and stress response. In this lecture I will present, based mainly on human studies but also on preclinical studies, the evidence for a role of the gut microbiota in the development of alcohol use disorder. I will show the first results of trials to test the effects of nutritional approaches to address these deficits.

Promising Neuroimmune Targets for Alcohol Use Disorder Pathology

Examination of adolescent cannabinoid vapour exposure effects on behavioural predictors of addiction and alcohol use disorder features in adult male and female rats

FENS Forum 2024

Alcohol Use Disorder Severity is Linked to Altered Functional Connectivity in Default Mode, Salience and Executive Control Networks

Axonal pathology in alcohol use disorders

Neurophysiological correlates of sub-dimensions of alcohol use disorder in rodents

Ventral pallido-subthalamic adaptations underlying pathological decision making in alcohol use disorders

Combined treatment with the glycine transporter-1-inhibitor Org24598, varenicline, and bupropion as a new pharmacological treatment concept for alcohol use disorder

FENS Forum 2024

Microglial activation in the anterior cingulate cortex: A biological marker of early adverse events and future vulnerability to develop alcohol use disorder

FENS Forum 2024

Selective inhibition of phosphodiesterase 7 enzymes reduces alcohol drinking and seeking in animal models of alcohol use disorders

FENS Forum 2024