cerebral blood flow

Taking the pulse of ageing: the role of cerebrovascular risk factors in ageing and dementia

Cerebrovascular support is critical for healthy cognitive ageing. Reduced cerebral blood flow in ageing is caused, among other things, by hypertension, arteriosclerosis (i.e. stiffening of the arteries) and plaque formation. Arterial stiffness is predictive of cognitive decline, is a critical risk factor for cerebrovascular accidents, and has been linked to heightened risks for Alzheimer’s Disease and other forms of dementia. The elasticity of cerebral arteries is influenced by lifestyle factors, including cardiorespiratory fitness. Monica will discuss data obtained in their laboratory with new noninvasive measures of cerebrovascular health (pulse-DOT, a diffuse optical tomographic method for studying cerebral arteriosclerosis), in conjunction with structural and functional brain measures and cognitive assessments. These findings support a model in which localised changes in arteriosclerosis lead to specific profiles of structural, functional, and cognitive declines, paving a way to individualised interventions.

Cerebral blood flow alterations in very preterm-born adults

Partial Pressure of Oxygen and Cerebral Blood Flow in the Brains of Conscious, Freely Moving Rats During Hypoxemia

Simultaneous prenatal alcohol and cannabinoid exposure during the second trimester augments reductions in fetal cerebral blood flow from alcohol exposure alone

Stimulus and single neurons induced cerebral blood flow signals in Behaving Non-Human Primates

Cerebral blood flow and executive function changes in response to active and passive aerobic exercise

FENS Forum 2024