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SeminarNeuroscience

Computational models of spinal locomotor circuitry

Simon Danner
Drexel University, Philadelphia, USA
Jun 14, 2023

To effectively move in complex and changing environments, animals must control locomotor speed and gait, while precisely coordinating and adapting limb movements to the terrain. The underlying neuronal control is facilitated by circuits in the spinal cord, which integrate supraspinal commands and afferent feedback signals to produce coordinated rhythmic muscle activations necessary for stable locomotion. I will present a series of computational models investigating dynamics of central neuronal interactions as well as a neuromechanical model that integrates neuronal circuits with a model of the musculoskeletal system. These models closely reproduce speed-dependent gait expression and experimentally observed changes following manipulation of multiple classes of genetically-identified neuronal populations. I will discuss the utility of these models in providing experimentally testable predictions for future studies.

SeminarNeuroscience

Monitoring gait outcomes in rehabilitation with human pose estimation and wearable sensors

Ronald James Cotton
Center for Bionic Medicine, Shirley Ryan AbilityLab, Chicago
Jan 26, 2023
SeminarNeuroscienceRecording

Functional gait disorders: a sign-based approach

Jorik Nonnekes
Radboud University Medical Centre, Nijmegen, the Netherlands
Oct 12, 2021
SeminarNeuroscienceRecording

How to assess and manage spastic gait in rare diseases?

Gál Ota
General University Hospital in Prague, Czech Republic
Sep 10, 2020
ePosterNeuroscience

Modeling gait dynamics with switching non-linear dynamical systems

Heike Stein, Njiva Andrianarivelo, Clarisse Batifol, Jeremy Gabillet, Ali Jalil, Michael Graupner, N. Alex Cayco Gajic

Bernstein Conference 2024

ePosterNeuroscience

The emergence of fixed points in interlimb coordination underlies the learning of novel gaits in mice

Heike Stein,Andry Andrianarivelo,Jeremy Gabillet,Clarisse Batifol,Michael Graupner,N Alex Cayco Gajic

COSYNE 2022

ePosterNeuroscience

Cerebellar Purkinje cells control movement and their degeneration causes specific gaiting defects

Laurens Bosman, Lorenzo Bina, Dick Jaarsma, Chris De Zeeuw

FENS Forum 2024

ePosterNeuroscience

Development of a novel VR-based system for quantitative assessment of freezing of gait in Parkinson disease

Shota Emoto, Kazuhide Seo, Toru Ishii, Kanako Abe, Masahito Miki, Toshimasa Yamamoto, Masayuki Hara

FENS Forum 2024

ePosterNeuroscience

Exploring the interplay of gait and anxiety in a synucleinopathy model of Parkinson’s disease

Michael Schellenberger, Alexia Lantheaume, Dennis Doll, Konstantin Kobel, Silvia Rodriguez-Rozada, Philip Tovote

FENS Forum 2024

ePosterNeuroscience

Functional stimulation system for rehabilitation of gait and driving neural plasticity after spinal cord injury

Sònia Trujillo Vázquez, Guillermo García Alías, Xavier Navarro Acebes

FENS Forum 2024

ePosterNeuroscience

Longitudinal study of delayed cerebral ischemia in mice using daily functional ultrasound (fUS) imaging and gait analysis

Barthe Louis, Clement Rombi, Samuel Le Meur-Diebolt, Jean-Charles Mariani, Aurelien Mazeraud, Zsolt Lenkei

FENS Forum 2024

ePosterNeuroscience

Neuromodulation robustly tunes rhythmic patterns in a fixed connectome: Application to gait control

Arthur Fyon, Pierre Sacré, Guillaume Drion

FENS Forum 2024

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