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Why nanoscale (co-)organization of glutamate receptors is essential to understand synaptic physiology?
Presynaptic plasticity in hippocampal circuits
Christophe Mulle is a cellular neurobiologist with expertise in electrophysiology of synaptic transmission and an international leader in studies on glutamate receptors and hippocampal synaptic plasticity. He was among the first to identify and characterize functional nicotinic receptors in the mammalian brain while working in the laboratory of Jean-Pierre Changeux at the Pasteur Institute. He then generated knock-out mice for KAR subunits at the Salk Institute in the laboratory of Steve Heinemann, which have proven to be instrumental for understanding the function of these elusive glutamate receptors in synaptic function and plasticity.
Group III metabotropic glutamate receptors at the inner hair cell ribbon synapse in the cochlea
Immunocytochemical localization of AMPA glutamate receptors subtype GluR2&3 in the squid optic lobe
Metabotropic glutamate receptors group II (mGlur2/3) agonists reduced apoptosis and regulated BDNF, GDNF, and TGF – beta levels in hypoxic-ischemic injury in neonatal rats
Photoactivation of individual synapses in vivo with covalent photoswitches targeting endogenous glutamate receptors
Secreted Olfactomedin1-3 control synaptic incorporation of AMPA-type glutamate receptors
Studying the Specificity of Autoantibodies against Glutamate Receptors and Auxiliary Proteins in Rasmussen’s Encephalitis
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