← Back

Interoceptive Signals

Topic spotlight
TopicNeuro

interoceptive signals

Discover seminars, jobs, and research tagged with interoceptive signals across Neuro.
1 curated item1 Seminar
Updated over 4 years ago
1 items · interoceptive signals

Latest

1 result
SeminarNeuroscience

Contrasting neuronal circuits driving reactive and cognitive fear

Mario Penzo
NIMH
Jun 28, 2021

The last decade in the field of neuroscience has been marked by intense debate on the meaning of the term fear. Whereas some have argued that fear (as well as other emotions) relies on cognitive capacities that are unique to humans, others view it as a negative state constructed from essential building blocks. This latter definition posits that fear states are associated with varying readouts that one could consider to be parallel processes or serial events tied to a specific hierarchy. Within this framework, innate defensive behaviors are considered to be common displays of fear states that lie under the control of hard-wired brain circuits. As a general rule, these defensive behaviors can be classified as either reactive or cognitive based on a thread imminence continuum. However, while evidence of the neuronal circuits that lead to these divergent behavioral strategies has accrued over the last decades, most literature has considered these responses in isolation. As a result, important misconceptions have arisen regarding how fear circuits are distributed in the brain and the contribution of specific nodes within these circuits to defensive behaviors. To mitigate the status quo, I will conduct a systematic comparison of brain circuits driving the expression of freezing and active avoidance behavior, which I will use as well-studied proxies of reactive and cognitive fear, respectively. In addition, I propose that by integrating associative information with interoceptive and exteroceptive signals the central nucleus of the amygdala plays a crucial role in biasing the selection of defensive behaviors.

interoceptive signals coverage

1 items

Seminar1
Domain spotlight

Explore how interoceptive signals research is advancing inside Neuro.

Visit domain