muscle cells
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Reverse engineering neural control of movement in Hydra
Hydra is a fascinating model organism for neuroscience. It is transparent; new genetic lines allow one to image activity in both neurons (Dupre and Yuste, 2017) and muscle cells (Szymanski and Yuste, 2019) ; it exhibits rich behavior, and it continually rebuilds itself. Hydra’s fairly simply physical structure as a two-layered fluid-filled hydrostat and the accessibility of information about neural and muscle activity opens the possibility of a complete model of neural control of behavior. This requires understanding the transformations that occur in the muscle cell layers and a biomechanical model of the body column. We show that we can use this modeling to reverse engineer how neural activity drives behavior.
TARGETING MALAT1 LNCRNA TO MODULATE AUTOPHAGY AND MYOGENESIS IN IPSC-DERIVED MUSCLE CELLS: A NANO-NUCLEAR STRATEGY FOR C9ORF72-ALS
FENS Forum 2026
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