neural crest

↗ Clonal analysis at single cell level helps to understand neural crest development

Clonal analysis at single cell level helps to understand neural crest development

Recent research on the neural crest has revealed the multipotency and plasticity of nerve-associated Schwann cell precursors, which can differentiate into diverse cell types, including parasympathetic neurons, neuroendocrine cells, and mesenchymal stem cells. These findings challenge the traditional view of peripheral nerves, highlighting their role as niches for migratory progenitor cells that contribute to tissue formation and regeneration.

Adult neurogenesis in mouse hippocampus

Dr. Aixa V. Morales has been working for more than 20 years in the field of Developmental Biology and from 2005, she is the PI of the laboratory on “Molecular Control of Neurogenesis” at Cajal Institute. Along these years, she has contributed to understanding the control of neurogenesis during development, the dorsoventral specification of neural progenitors, and the temporal control of the migration of neural crest cells. More recently, her lab interest moved towards understanding modulation of adult neurogenesis. Her lab current interest is the control of quiescence, as a mechanism of long-term neural stem cell maintenance in adult niches.

Endocytic receptor LRP2: a new role in the neural crest cell dynamics

Migratory neurons of the human cephalic ectoderm and the neural crest

Single-cell RNA sequecing in mouse reveals that Schwann cell precursors represent a Neural Crest-like hub state with biased multipotency

Coffee-derived exosome-like nanoparticles affect cell viability and cell death differently of neural crest-derived and glial tumor cells

FENS Forum 2024