neuroimmune mechanisms
Latest
Neuroimmune interactions in Cardiovascular Diseases
The nervous system and the immune system share the common ability to exert gatekeeper roles at the interfaces between internal and external environment. Although interaction between these two evolutionarily highly conserved systems is long recognized, the pathophysiological mechanisms regulating their reciprocal crosstalk in cardiovascular diseases became object of investigation only more recently. In the last years, our group elucidated how the autonomic nervous system controls the splenic immunity recruited by hypertensive challenges. In my talk, I will focus on the molecular mechanisms that regulate the neuro-immune crosstalk in hypertension. I will elaborate on the mechanistic insights into this brain-spleen axis led us uncover a new molecular pathway mediating the neuroimmune interaction established by noradrenergic-mediated release in the spleen of placental growth factor (PlGF), an angiogenic growth factor potentially targetable with pharmacological approaches.
PERIPHERAL NEUROIMMUNE MECHANISMS UNDERLYING MECHANICAL ITCH HYPERSENSITIVITY ASSOCIATED WITH AUTISM SPECTRUM DISORDERS
FENS Forum 2026
neuroimmune mechanisms coverage
2 items
Share your knowledge
Know something about neuroimmune mechanisms? Help the community by contributing seminars, talks, or research.
Contribute contentExplore how neuroimmune mechanisms research is advancing inside Neuroscience.
Visit domain