Topic: presynaptic plasticity

Presynaptic plasticity in hippocampal circuits

Christophe Mulle is a cellular neurobiologist with expertise in electrophysiology of synaptic transmission and an international leader in studies on glutamate receptors and hippocampal synaptic plasticity. He was among the first to identify and characterize functional nicotinic receptors in the mammalian brain while working in the laboratory of Jean-Pierre Changeux at the Pasteur Institute. He then generated knock-out mice for KAR subunits at the Salk Institute in the laboratory of Steve Heinemann, which have proven to be instrumental for understanding the function of these elusive glutamate receptors in synaptic function and plasticity.

Physiological role of the full-length amyloid precursor protein (APP) in presynaptic plasticity and information transfer within hippocampal CA3 circuits

Role of presynaptic plasticity at mossy fiber-CA3 synapses: consequences of Syt7 abrogation in DG cells on CA3 circuits and memory encoding