sympathetic control
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Sympathetic control of lymph node function
Peripheral nerve injury can cause debilitating disease and immune-cell mediated destruction of the affected nerve. While the focus of most studies has been on the nerve-degenerative response, the effect of loss of innervation on lymph node function is largely unclear. Here, I will discuss the cellular and molecular events caused by local denervation and loss of direct neural input to the popliteal lymph node that induce an inflammatory response and lymph node expansion.
DYSREGULATION OF THE AGRP–PVH CIRCUIT DISRUPTS SYMPATHETIC CONTROL OF BONE MARROW IN EXPERIMENTAL MULTIPLE SCLEROSIS
FENS Forum 2026
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