Topic: ventricular zone

Stem Cells in the Adult Brain: Regulation and Diversity

Neural stem cells reside in the adult mammalian brain. The ventricular-subventricular zone (V-SVZ) gives rise to olfactory bulb neurons, as well as small numbers of glia throughout life. Adult V-SVZ neural stem cells dynamically integrate intrinsic and extrinsic signals to either maintain the quiescent state or to become activated to divide and generate progeny. I will present our recent findings highlighting adult neural stem cell heterogeneity, including the identification of novel gliogenic domains and cell types, and the key roles of physiological state and long-range signals in the regulation of regionally distinct pools of adult neural stem cells.

FGF18 – a new player in the regulation of adult Subventricular zone (SVZ) neurogenesis

Growth/differentiation factor 15 influences primary cilia in neural stem cells in the ventricular-subventricular zone but not in the subgranular zone

Outcomes of beta-amyloid 1-42 exposure on the neurogenic subventricular zone of the adult brain at Alzheimer's dieses model

Sexually-dimorphic cell and gene regulatory networks in the median-eminence and periventricular zone of the tuberal region of the hypothalamus