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On places and borders in the brain
While various forms of cells have been found in relation to the hippocampus cognitive map and navigation system, how these cells are formed and what is read from them is still a mystery. In the current lecture I will talk about several projects which tackle these issues. First, I will show how the formation of border cells in the coginitive map is related to a coordinate transformation, second I will discuss the interaction between the reward system (VTA) and the hippocampus. Finally I will describe a project using place cells as a proxy for associative memory for assessing deficits in Alzheimer’s disease.
CHRONIC STRESS REPROGRAMS SYNAPTIC AND TRANSCRIPTIONAL SIGNATURES OF THE MPFC-VTA CIRCUITRY TO IMPAIR COGNITION
FENS Forum 2026
FUNCTIONAL ROLE OF VTA NEURONAL PROJECTIONS TO THE BNST IN THREAT AND ANXIETY PROCESSING
FENS Forum 2026
ANTAGONISTIC CODING OF ENERGY INTAKE AND ENERGY EXPENDITURE BY VTA DOPAMINE SUBPOPULATIONS
FENS Forum 2026
TEMPORAL ROLES OF VTA DOPAMINE NEURONS IN FEAR LEARNING, EXTINCTION, AND POST-LEARNING SLEEP
FENS Forum 2026
PARTNER IDENTITY EFFECTS ON CEA-VTA CIRCUIT FUNCTION DURING SOCIAL INTERACTION
FENS Forum 2026
NUCLEUS ACCUMBENS CONTROL OF VTA MODULATION OF HIPPOCAMPAL MEMORY CONSOLIDATION
FENS Forum 2026
Effects of VTA activation on the recovery process following myocardial infarction
Locomotor control by theta-range activation of glutamatergic MSDB to VTA projections
Neural signaling in the VTA-accumbens axis correlated with cannabis extract effects on methamphetamine conditioned place preference in mice
Nicotinic receptors promote susceptibility to social stress in female mice linked with neuroadaptations within VTA dopamine neurons
Postnatal IL-4 administration induces long-term dysfunction in cerebellar-VTA connectivity
Progressive hyperpolarization-activated cation current (Ih) reduction: a response mechanism to decrease cocaine-induced excitability in VTA DA neurons
The survival of VTA dopamine neurons is associated with upregulation of Ca2+ binding proteins in the Tg2576 model of Alzheimer’s Disease
Vicarious reward signals in the VTA drive prosocial choices in rats
Anatomofunctional characterization of the tail of the ventral tegmental area (tVTA/RMTg) in mice
FENS Forum 2024
Newly Formed Synapses Between VTA Projections and ACC Pyramidal Neurons in Response to Chronic Social Defeat Stress Differentiate Stress Susceptible From Stress Resilient Mice
Dissecting the effects of distinct VTA projections on peripheral immunity
FENS Forum 2024
Dynamic dynorphin release in the VTA during appetitive and aversive associative learning
FENS Forum 2024
Glutamatergic and GABAergic mu-opioid receptor VTA neurons differentially modulate motivational and somatic consequences of fentanyl use
FENS Forum 2024
Mapping the neural circuitry: LC-NE neurons and their connections to VTA and Raphe nuclei
FENS Forum 2024
Maternal Fmr1 deficiency dysregulates offspring sociability and oxytocinergic signaling in the VTA
FENS Forum 2024
Opposite coding of competing rewards by VTA dopamine neurons
FENS Forum 2024
Stimuli-evoked noradrenergic activity in the VTA drives phasic dopamine release in the nucleus accumbens – preliminary results
FENS Forum 2024
Worry not, the VTA has the BNST under control… or does it?
FENS Forum 2024
VTA circuitry sustains opposite responses of dopaminergic neurons to drugs of abuse
FENS Forum 2024
VTA dopamine neurons signal phasic and ramping reward prediction error in goal-directed navigation
COSYNE 2022
Chronic nicotine alters motivational value of natural rewards through circuit-based alterations in VTA dopamine neurons
VTA circuitry sustains opposite responses of dopaminergic neurons to drugs of abuse
Contribution of GirK channels expressed in VTA GABAergic neurons to anxiety, social behaviors and hippocampal-dependent memory
VTA dopamine neurons orthogonally encode motivated behaviours
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