Physiology seminars
June 2021
Some new insights into the central sensing of nutritional state and somatic stress
Stephen O'Rahilly· Wellcome-MRC Institute of Metabolic Science, University of Cambridge
Mon, Jun 28 · 15:00 UTC · Online
This talk will focus on two areas. I will firstly discuss some new data, starting with insights from rare human genetic variants, which helps to clarify the role of the central melanocortin system in the acquisition of nutrients and their disposition into growth, the acquisition of lean mass and sexual maturation . I will then discuss some aspects of the emerging biology of GDF15; a sentinel hormone conveying information regarding a range of somatic stresses to the brain.
End of results.