Validation of template-based attenuation correction for in vivo quantification of the serotonin transporter using positron emission tomography
Christian Milz, Murray Bruce Reed, Matej Murgaš, Andreas Hahn, Rupert Lanzenberger · FENS Forum 2024
Attenuation correction (AC) is an essential procedure for accurately quantifying molecular targets in positron emission tomography (PET). As an alternative to computed tomography (CT), a variety of approaches utilizing magnetic resonance (MR) imaging has been implemented. Since most of these are computationally expensive (i.e. take several hours), we improved upon the MaxProb[1] algorithm for use in neuroimaging. 40 paired CTs and T1 weighted MR images from a previous study[2] were normalized to Montreal Neurological Institute space. Each CT was then segmented into air, soft tissue and bone. S
ePoster · Neuroscience