Microprinted 3D scaffolds for repair of spinal cord injury
Volodymyr Medvediev, Sergei Grebenyuk, Yevhenii Sheremet, Ibrahim Abdalla, Valeriia Ustymenko, Tetiana Pivneva, Adrian Ranga, Pavel Belan, Nana Voitenko · FENS Forum 2024
3D printed scaffold represents a promising approach for treatment of spinal cord injury (SCI). Here we suggest an innovative biotechnological approach for free-form 3D printing of scaffolds with a biomimetic architecture at a spatial resolution up to a micrometer, which were used for implantation in treatment of SCI in one-month-old Wistar rats. The approach is based on 2-photon photopolymerization of organic polymers and is scalable to lesion geometries. The scaffolds were implemented as multiple densely packed parallel micro-tunnels (~50 μm) running through their whole length. Having thin wa
ePoster · Neuroscience