Microstructural characterization of brain organoids
Federico Tozzi, Gemma Gomez-Giro, Sonia Cerchio, Nicola Vanello, Arti Ahluwalia, Jens Schwamborn, Chiara Magliaro · FENS Forum 2024
Human brain organoids are 3D self-assembling constructs obtained from human pluripotent stem cells, differentiating, and recapitulating the structural and functional complexity of the human brain. Quantitatively describing the cellular spatial arrangement within these constructs and their morphology is important to assess their structural resemblance to the human brain, and thus effectively demonstrating their ability to recapitulate the brain salient microstructural features. Thanks to pluripotent stem cell technology, brain organoids obtained from cells of healthy and diseased patients will
ePoster · Neuroscience