Topic: AAVPHP.eB

The salamander axolotl (Ambyostoma mexicanum) is a model for studying nervous system evolution, development, and regeneration. Axolotls can regenerate injuries to the central and peripheral nervous system making them an ideal model to study formation and regeneration of neuronal circuits. Tools to visualize and manipulate cells of the axolotl nervous system with high efficiency, spatial and temporal precision are therefore greatly required. Recombinant adeno-associated viruses (AAVs) are frequently used for in vivo gene transfer of the nervous system but virus-mediated gene delivery to the axo