Topic: Actb

To facilitate rapid changes in protein composition in axons and dendrites, neurons can translate mRNAs into proteins at distal sites. This machinery requires long-range transport of specific mRNAs, which are packaged into granules by RNA-binding proteins and carried by kinesin motor proteins along microtubule. Local mRNA translation is crucial for dendritic spine development and plasticity. Nonetheless, whether different mRNAs are distributed in a specific manner near synapses and how is their localization regulated after synaptic stimulation are not well-characterized. Consistent with previou