Examination of adolescent cannabinoid vapour exposure effects on behavioural predictors of addiction and alcohol use disorder features in adult male and female rats
Jairo Steffan Acosta-Vargas, Natalia De las Heras-Martinez, Lucia Garrido-Matilla1, Maria Roca-Outeiro, Natalia Puig-Martínez, Ana Belen Sanz-Martos, Shishir Baliyan, Marcos Ucha, Alejandro Higuera-Matas · FENS Forum 2024
Cannabis is a widely used drug during adolescence, a particularly vulnerable neurodevelopmental period, posing concerns about predisposing users to substance (especially, alcohol) use disorders later in life. This study investigates whether adolescent cannabinoid exposure (ACE) in vapour form facilitates the emergence of alcohol use disorder in adulthood. In addition, we also analysed certain behavioural predictors of addiction and how their relationship with specific aspects of alcohol consumption changes after ACE.Male and female rats were exposed to different THC and CBD concentrations (THC
ePoster · Neuroscience