Sex-dependent differences of short-term aerobic endurance exercise on systemic LPS-induced inflammation and microglial activation in young C57BL/6J mice
Joana Augusto, Zsuzsanna Barad, Áine Kelly · FENS Forum 2024
Regular aerobic endurance exercise has been considered to have neuroprotective effects, with recent evidence suggesting its potential role in modulating inflammatory mediators and microglia states and functions in the central nervous system. Most of the published data to date have been generated using male mice, hence the effects of both exercise and experimentally-induced neuroinflammation are less well-investigated, and hence are less well-understood in female mice.Here, we investigated the impact of 7 consecutive days of low-to-moderate-intensity treadmill running on microglial activation i
ePoster · Neuroscience