Comparison of histological procedures and antigenicity of human postmortem brains fixed with solutions used in gross-anatomy laboratories
Eve-Marie Frigon, Amy Gérin-Lajoie, Mahsa Dadar, Denis Boire, Josefina Maranzano · FENS Forum 2024
Brain banks provide small tissue samples to researchers, while gross-anatomy laboratories could provide complete brains, but these are preserved with solutions appropriate for gross-dissection, different from the classic neutral-buffered-formalin (NBF) used in brain banks. Our previous work in mice showed that two gross-anatomy laboratory solutions, a saturated-salt-solution (SSS) and an alcohol-formaldehyde-solution (AFS), preserve antigenicity of the main cellular markers. Our goal is now to compare the histology and antigenicity preservation of human brains fixed following: 1-brain bank pra
ePoster · Neuroscience