The dynamical regime of mouse visual cortex shifts from cooperation to competition with increasing visual input
William Podlaski,Lloyd Russell,Arnd Roth,Brendan Bicknell,Michael Hausser,Christian Machens · COSYNE 2022
Recent experiments have revealed that visual cortex operates as an inhibition-stabilized network (ISN), in which unstable excitatory coupling is balanced by strong inhibition. Computational models like the stabilized supralinear network (SSN) describe the mechanisms behind this regime, and also postulate that a transition occurs from non-ISN to ISN dynamics with increasing visual input. However, while some studies find input-dependent effects that support a shift in dynamical regime, others have shown ISN-like dynamics in the spontaneous state, leaving open questions about the existence and na
Thu, Mar 17, 2022