Importance of glial CB1R in the regulation of neuromuscular repair
Sophie Charron, Roberta Piovesana, Luigi Bellocchio, Giovanni Marsicano, Richard Robitaille · FENS Forum 2024
Intricate and extended mechanisms are in place to allow for repair following injuries of the peripheral nervous system (PNS), particularly at the neuromuscular junction (NMJ). Type 1 endocannabinoid receptors (CB1R) may be involved in the repair process owing to their presence in the PNS and at the NMJ and given their role in axonal growth and neuronal plasticity. Owing to the role of perisynaptic Schwann cells, glial cells at the NMJ, in the regulation of NMJ repair following injury, we postulate that CB1R participate in NMJ denervation and reinnervation processes and that this regulation may
ePoster · Neuroscience